Galien is a village in Berrien County in the U.S. state of Michigan. The population was 593 at the 2000 census. The village is located within Galien Township. The village provides its own sewer utility.
The founder of the village of Galien was George A. Blakeslee. Born in Pennsylvania, he came to Galien Township in 1853. He platted Galien village in 1861, and it was incorporated in 1879.
Blakeslee operated a sawmill at the site of present-day Galien, and established a general store. He purchased several thousand acres in the vicinity of the village and harvested the timber for his sawmill operation. For many years after Galien was established, he was president of the village.