Antagonist Cafe

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2727 S 12th St
Saint Louis, MO 63118

Antagonist Cafe, nestled in the heart of Saint Louis, MO, offers a unique culinary experience for locals and visitors alike. Boasting a prime location just across from the renowned Anheuser-Busch Brewery Tour, this cafe provides a cozy ambiance to enjoy delicious treats.

From delectable pastries to aromatic coffees, Antagonist Cafe serves up a delightful array of menu items to satisfy any craving. Each visit promises a welcoming atmosphere where patrons can indulge in freshly brewed beverages and homemade delicacies.

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Reviews

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4.536 reviews
Photo of Mindy P.
Mindy P.
10/31/2025

What a great spot for coffee! If you are in the area, you have to check it out! I am limiting my caffeine intake so went for some tea, it tasted great and I feel like I got a lot of bang for...

Photo of Kimberly W.
Kimberly W.
10/16/2025

I heard about this place months ago, but didn't get a chance to actually check them out until recently. They are located in a former jail and incorporate this into the theme of the shop, so it's...

Photo of Carri N.
Carri N.
10/1/2025

Well repurposed old police station now cafe and board game businesses occupy this space. Got a Café au lait with a nice creamy foam on top. First time having one of those and it was pretty...

Photo of Devon B.
Devon B.
12/28/2025

This place is awesome! Gluten free and gluten filled options for delicious treats are available! Great drinks! Plenty of cool places to sit! Very nice staff! HIGHLY recommend coming here - even...

Photo of Whitney D.
Whitney D.
8/24/2025

This old Jail now turned into a coffee shop is very clever. It was my first time here and while walking around there is a little area in the back where you can sit and enjoy your coffee in what is...

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