Cosby is a village in Andrew County, Missouri, United States. The population was 143 at the 2000 census. It is part of the St. Joseph, MO–KS Metropolitan Statistical Area.
Cosby is located at 39°51′49″N 94°40′47″W / 39.86361°N 94.67972°W / 39.86361; -94.67972 (39.863522, -94.679738).
According to the United States Census Bureau, the village has a total area of 0.1 square miles (0.2 km²), all of it land.