Prairie Home, MO
Prairie Home is a town, with legal status as a city, in Cooper County, Missouri, United States. The population was 220 at the 2000 census.
Prairie Home is located at 38°48′47″N 92°35′23″W / 38.81306°N 92.58972°W / 38.81306; -92.58972 (38.813012, -92.589786).
According to the United States Census Bureau, the city has a total area of 0.4 square miles (1.0 km²), all of it land.