Mendenhall is a city in Simpson County, Mississippi, United States. The population was 2,555 at the 2000 census. It is the county seat of Simpson County. Mendenhall is part of the Jackson Metropolitan Statistical Area.
Mendenhall is located at 31°57′40″N 89°52′3″W / 31.96111°N 89.8675°W / 31.96111; -89.8675 (31.961160, -89.867558).
According to the United States Census Bureau, the city has a total area of 5.3 square miles (13.8 km²), of which, 5.3 square miles (13.8 km²) of it is land and 0.04 square miles (0.1 km²) of it (0.37%) is water.