Ripley is a city in Tippah County, Mississippi, United States. The population was 5,478 at the 2000 census. It is the county seat of Tippah County.
Colonel William Clark Falkner, great-grandfather of authors William Faulkner and John Faulkner, was a prominent resident of Ripley in the mid to late-19th century. W.C. Falkner's exploits in and around Ripley served as the model for Faulkner's character of Colonel John Sartoris.
Ripley is located at 34°43′57″N 88°56′49″W / 34.7325°N 88.94694°W / 34.7325; -88.94694 (34.732363, -88.947055).