Tishomingo is a town in Tishomingo County, Mississippi, United States. The population of the city of Tishomingo was 316 at the 2000 census. Its ZIP code is 38873.
Tishomingo is named after Chief Tishomingo of the Chickasaw tribe, who signed the Treaty of Pontotoc in 1832. He died on the infamous 'Trail of Tears' and is buried in Little Rock, Arkansas . His son, Iuka, is the namesake of the county seat of Tishomingo, County, Mississippi.