Mayodan is a town in Rockingham County, North Carolina, in the United States. It is a manufacturing site for Bridgestone Aircraft Tire and General Tobacco. Washington Mills Company, later Tultex, operated a textile mill in Mayodan until 1999.
The town is named for two rivers that converge nearby, the Mayo and the Dan, and is the only town in the world with this name.
Mayodan is located at 36°24′51″N 79°58′15″W / 36.41417°N 79.97083°W / 36.41417; -79.97083 (36.414089, -79.970849).