Cairo is a village in Hall County, Nebraska, United States. The population was 790 at the 2000 census. It is part of the Grand Island, Nebraska Micropolitan Statistical Area.
Cairo is located at 41°00′01″N 98°36′29″W / 41.000409°N 98.608083°W / 41.000409; -98.608083 (41.000409, -98.608083).
According to the United States Census Bureau, the village has a total area of 0.5 square miles (1.4 km2), all of it land.