Creighton is a city in Knox County, Nebraska, United States. The population was 1,194 at the 2010 census. The city was named in honor of John A. Creighton.
Creighton is located at 42°27′54″N 97°54′26″W / 42.465°N 97.90722°W / 42.465; -97.90722 (42.465112, -97.907191).
According to the United States Census Bureau, the city has a total area of 1.2 square miles (3.1 km²), all of it land.