Mineville-Witherbee is a census-designated place and region of the Town of Moriah in Essex County, New York, United States. The population was 1,747 at the 2000 census.
The CDP is composed of the two hamlets of Mineville and Witherbee. They are located in the northern part of Moriah, northwest of Port Henry.
Mineville-Witherbee is located at 44°5′13″N 73°31′28″W / 44.08694°N 73.52444°W / 44.08694; -73.52444 (44.086842, -73.524480).