Prattsville is a town in Greene County, New York, United States. The population was 700 at the 2010 census.
The Town of Prattsville is in the northwest part of the county.
The town was first settled around 1763, and the region was then called "Schoharie Kill." An attempt during the American Revolution by the British and their Tory allies to drive the settlers out was thwarted when they were defeated by the settlers.