Sayville is a hamlet and CDP in Suffolk County, New York, (USA). Located on the south shore of Long Island in the Town of Islip, the population of the CDP was 16,735 at the time of the 2000 census.
The earliest known inhabitants of Sayville were the Secatogue tribe, of the Algonquian peoples.
Sayville was founded by John Edwards (b. 1738, East Hampton, New York). He built his home, the first in Sayville, in 1761, located at what is now the northwest corner of Foster Ave. and Edwards St. The house was destroyed by fire in March, 1913. Another man, John Greene, settled what's now known as West Sayville in 1767.