Tuttle is a city in Grady County, Oklahoma, United States. The population was 4,294 at the 2000 census.
Tuttle is a largely agricultural community with a focus on wheat, cotton, corn, alfalfa hay, Bermuda grass hay, and cattle. Nearby Braum's Dairy, the largest farm in the area, is located just outside the city's limits and has a market presence spanning several states. The city serves as a minor bedroom community of Oklahoma City.
The town was named in 1902 after a local cattleman and rancher, J. H. (Jim) Tuttle.