Jerome is a census-designated place (CDP) in Somerset County, Pennsylvania, United States. The population was 1,068 at the 2000 census. It is part of the Johnstown, Pennsylvania, Metropolitan Statistical Area. Jerome is part of the municipality of Conemaugh Township, Somerset County, Pennsylvania, as are the nearby towns of Davidsville, Thomas Mills, Tire Hill, Seanor, Hiyasota and part of Holsopple.
Jerome is located at 40°12′36″N 78°59′8″W / 40.21°N 78.98556°W / 40.21; -78.98556 (40.210047, -78.985652).
According to the United States Census Bureau, the CDP has a total area of 2.6 square miles (6.8 km²), all of it land.