Luzerne is a borough located five miles (eight km) north of Wilkes Barre in Luzerne County, Pennsylvania near the Susquehanna River. In the early years of the twentieth century, it had coal mines, a foundry, drill factories, flour and feed mills, canning factory, silk mill, etc. In 1900, 3,817 people lived here; in 1910, 5,425 people lived here; and in 1940, 7,082 people lived in Luzerne. The population was 2,952 at the 2000 census.
Luzerne is located at 41°17′2″N 75°53′34″W / 41.28389°N 75.89278°W / 41.28389; -75.89278 (41.283780, -75.892890).
According to the United States Census Bureau, the borough has a total area of 0.7 square miles (1.8 km²), all of it land.