Millville is a borough in Columbia County, Pennsylvania, United States. It is part of the Bloomsburg–Berwick Micropolitan Statistical Area.
John Eves, a native of Ireland living in Mill Creek Hundred, Delaware, is thought to have been one of the first white men to visit the Greenwood Valley and Little Fishing Creek area in 1770. (One account of this visit indicates that he purchased a sizeable portion of the land he explored in the area from the Indians who had served as his guides on this trek.) Although he returned to Delaware after this initial visit, he returned the following year with his son Thomas and built a log cabin on the property. The entire Eves family arrived the next year, in 1772, and began tilling the fields adjacent to the cabin as soon as they could be cleared.