Founded in 1974, Synthes Inc. is one of the leading skeletal fixation companies in North America. It offers a range of medical instruments and implants to several hospitals throughout the United States. The company operates an orthopedic division that designs and markets products that are used for face, skull and spine surgeries. It also manages Synthes Spine Company, which offers products for the treatment of degenerative spine disorders. Synthes operates 24 hours per day, seven days a week. The company manages manufacturing facilities in Colorado, Pennsylvania and New York, as well as Germany. It additionally maintains distribution and technical centers.