Cameron is a town in Calhoun County, South Carolina, United States. The population was 449 at the 2000 census. It is part of the Columbia, South Carolina Metropolitan Statistical Area.
Cameron is located at 33°33′27″N 80°42′55″W / 33.5575°N 80.71528°W / 33.5575; -80.71528 (33.557567, -80.715311).
According to the United States Census Bureau, the town has a total area of 3.1 square miles (8.1 km²), all of it land.