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Cope is a town in Orangeburg County, South Carolina, United States. The population was 107 at the 2000 census.
Cope is located at 33°23′N 81°0′W / 33.383°N 81°W / 33.383; -81 (33.3775, -81.0077).
According to the United States Census Bureau, the town has a total area of 0.2 square miles (0.6 km²), all of it land.