Cottageville is a town in Colleton County, South Carolina, United States. The population was 707 at the 2000 census.
According to the United States Census Bureau, Cottageville has a total area of 3.2 square miles (8.2 km²), all of it land.
As of the census of 2000, there were 707 people, 274 households, and 206 families residing in the town. The population density was 222.2 people per square mile (85.8/km²). There were 310 housing units at an average density of 97.4 per square mile (37.6/km²). The racial makeup of the town was 85.71% White, 11.88% African American, 0.42% Native American, 0.42% Asian, 0.14% Pacific Islander, 0.28% from other races, and 1.13% from two or more races. Hispanic or Latino of any race were 0.42% of the population.