Mitchell is a city in and the county seat of Davison County, South Dakota, United States. The population was 15,254 at the 2010 census. Mitchell was incorporated in 1881. It was named for Milwaukee banker Alexander Mitchell, President of the Chicago, Milwaukee, and St. Paul Railroad (Milwaukee Road).
Mitchell is the principal city of the Mitchell Micropolitan Statistical Area, which includes all of Davison and Hanson counties.
Mitchell is located at 43°42′50″N 98°1′35″W / 43.71389°N 98.02639°W / 43.71389; -98.02639 (43.713896, -98.026282), on the James River.