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De Smet is a city in and the county seat of Kingsbury County, South Dakota, United States. The population was 1,089 at the 2010 census. It was named for Belgian Father Pierre De Smet, a 19th-century Jesuit missionary who worked with Native Americans in the United States and its territories for most of his life.
De Smet was the childhood home of Laura Ingalls Wilder, the supercentenarian Walter Breuning, and the birthplace of author Rose Wilder Lane.
De Smet is located at 44°23′9″N 97°33′6″W / 44.38583°N 97.55167°W / 44.38583; -97.55167 (44.385871, -97.551703).