Upper Kirby is a commercial district in Houston, Texas, United States.
Upper Kirby contains many businesses, including restaurants. Upper Kirby is east of the Greenway Plaza, southwest of Neartown, north of the city of West University Place, and south of River Oaks.
Upper Kirby is considered to be in an area west of South Shepherd Drive, east of Buffalo Speedway, north of Bissonnet Street, and south of Westheimer Road.