Huntsville is a town in Scott County, Tennessee, United States. The population was 981 at the 2000 census. It is the county seat of Scott County.
Huntsville is located at 36°24′39″N 84°29′42″W / 36.41083°N 84.495°W / 36.41083; -84.495 (36.410732, -84.495124). The town is situated atop the Cumberland Plateau at just over 10 miles (16 km) west of the plateau's eastern escarpment. Huntsville's southern boundary is located along a series of cliffs overlooking New River, approximately 15 miles (24 km) upstream from the river's mouth along the Big South Fork of the Cumberland River. Huntsville is surrounded by low mountains and hills that comprise the southern section of the Cumberland Mountains.
Huntsville's town center is situated along Tennessee State Route 63 (Howard Baker Highway), although the town's municipal boundaries stretch westward to TN-63's junction with U.S. Route 27. TN-63 intersects Interstate 75 approximately 15 miles (24 km) east of Huntsville, near the base of the Cumberland Plateau.