Jackson is a city in Madison County, Tennessee, United States. The total population was 65,211 at the 2010 census. Jackson is the primary city of the Jackson, Tennessee metropolitan area, which is included in the Jackson-Humboldt, Tennessee Combined Statistical Area. Jackson is the county seat of Madison County, and its largest city.
Jackson is located at 35°37′59″N 88°49′15″W / 35.63306°N 88.82083°W / 35.63306; -88.82083 (35.633132, -88.820805).
According to the United States Census Bureau, the city has a total area of 49.5 square miles (128.2 km²).