Tiptonville is a town in and the county seat of Lake County, Tennessee, United States. Its population was 2,439 as of the 2000 census. It is also home to the Northwest Correctional Complex, a maximum security prison, known for once housing mass murderer Jessie Dotson, Jr.
According to the Tennessee Historical Society, Tiptonville was established in 1857 but was not incorporated until 1900.
Tiptonville was the scene of the surrender of Confederate forces at the end of the 1862 Battle of Island Number Ten in the American Civil War. The monument for this battle is located on State Route 22 approximately three miles north of Tiptonville - since the island itself, main scene of the battle, has been eroded by the flow of the Mississippi River and no longer exists.