Henderson is a city in Rusk County, Texas, United States. The population was 11,273 at the 2000 census. It is the county seat of Rusk County. Henderson is named for James Pinckney Henderson, the first governor of Texas.
The city has functioned as a major crossroads in Northeast Texas over the last two centuries, with several major highways passing through the business district of the town, including Texas State Highway 64, U.S. Route 79, Texas State Highway 43, Texas State Highway 42 and Texas State Highway 64.
Annual events in the city of Henderson include the Heritage Syrup Festival in November, celebrating the east Texas tradition of syrup making, and the East Texas Sacred Harp Convention in August.