Nacogdoches ( /ˌnækədoʊtʃɨs/ nak-ə-doh-chəs) is a city in Nacogdoches County, Texas, in the United States. The 2010 census recorded the city's population to be 32,996. It is the county seat of Nacogdoches County and is situated in East Texas. Nacogdoches is a sister city of Natchitoches, Louisiana.
Nacogdoches is the home of Stephen F. Austin State University and of the Association for Business Communication.
Nacogdoches made international headlines in February 2003, after receiving much of the Space Shuttle Columbia disaster debris.