Vanderbilt is a census-designated place (CDP) in Jackson County, Texas, United States. The population was 411 at the 2000 census.
Vanderbilt is located on Farm Road 616 in SE Jackson County. The town started up in 1904, built around the new railroad station of the old Mitchell spread in the George Ewing league. The railway through the town is the location of St. Louis, Brownsville, and Mexico Railway, and has served as a trade center for local farmers and traders. Many stores were built in Vanderbilt, and once, there was even a hotel installed in the town. As the town expanded, the old mail delivery system was no longer an easy means of carrage, so a Post Office was built in 1907 and kept serving through '88, when a new one was built (zip: 77991). By 1945, Vanderbilt had a population of 300 and about 10 stores and trading posts. In 1962, when the town population reached its all time climax of 900, the town experienced a decline in population, due to relocation and migration. By 1971, the town was back down to 667, where it remained stable until 1990. Then, there were only 5 stores remaining in town, and the population decreased by the hundreds.
Vanderbilt is located at 28°49′20″N 96°36′57″W / 28.82222°N 96.61583°W / 28.82222; -96.61583 (28.822110, -96.615708).