Independence is a town in Grayson County, Virginia, United States. The population was 971 at the 2000 census. It is the county seat of Grayson County. Independence is home to a major town celebration on July 4 every year, held in front of the 1908 courthouse. It features bluegrass and old-time music and dance, food, crafts and a wild pony sale. The courthouse is also the location of the Mountain Foliage Festival, held in the autumn and featuring a parade, crafts, arts and music, as well as a race in which contestants use outhouses, the Grand Privy Race.
Independence is located at 36°37′22″N 81°9′6″W / 36.62278°N 81.15167°W / 36.62278; -81.15167 (36.622906, -81.151735).
According to the United States Census Bureau, the town has a total area of 2.3 square miles (6.1 km²), all of it land.