Worthington is a town in Marion County, West Virginia, in the United States. The population was 170 at the 2000 census. Worthington was incorporated in 1893 and named for Colonel George Worthington, an early settler.
Worthington is located at 39°27′6″N 80°15′46″W / 39.45167°N 80.26278°W / 39.45167; -80.26278 (39.451617, -80.262755), along the West Fork River.
According to the United States Census Bureau, the town has a total area of 0.6 square miles (1.5 km²), all land.