Clare is a city in Clare and Isabella counties in the U.S. state of Michigan. Located primarily in Clare County, the city had a population of 3,173 at the 2000 census. North-south US 127 forms the eastern boundary for much of the city and has a junction with east-west US 10 on the east side of the city. US 10 connects with Midland, 33 miles (53 km) to the southeast, and with US 131 at Reed City, 44 miles (71 km) to the west. US 127 connects with Mount Pleasant, 13 miles (21 km) to the south, and with Harrison, 14 miles (23 km) to the north. M-115 has is southern terminus in downtown Clare.
According to the United States Census Bureau, the city has a total area of 3.2 square miles (8.3 km²), of which, 3.1 square miles (8.1 km²) of it is land and 0.1 square miles (0.2 km²) of it (2.80%) is water. There are four stoplights within the city limits of Clare.
As of the 2010 census, there were 3,159 people, 1,594 households in the city. The racial makeup of the city was 73.03% White, 9.51% African American, 1.14% Native American, 5.36% Asian, 1.14% from other races, and 1.69% from two or more races. Hispanic or Latino of any race were 8.13% of the population.