Constantine is a village in St. Joseph County in the U.S. state of Michigan. The population was 2,095 at the 2000 census. The village is located within Constantine Township. It is on U.S. Highway 131, leading to Kalamazoo to the north and to the Indiana Toll Road six miles to the south. The non-navigable St. Joseph River passes through it toward Lake Michigan. The telephone provider is Verizon and the electric provider is AEP Indiana Michigan Power.
Constantine is the birthplace of Harry Hill Bandholtz, US Brigadier General in World War I and head of the US Military Mission to Hungary.
According to the United States Census Bureau, the village has a total area of 1.7 square miles (4.5 km²), of which, 1.6 square miles (4.2 km²) of it is land and 0.1 square miles (0.3 km²) of it (5.81%) is water.