Hydro is a town in Caddo and Blaine counties in the U.S. state of Oklahoma. The population was 969 at the 2010 census.
Hydro was home to Lucille Hamons, a Route 66 icon dubbed "The Mother of the Mother Road." Her motel and gas station still stand on Old Route 66 just west of Hydro. A modern replica of the station, with a large restaurant attached, is in nearby Weatherford.
In downtown Hydro, an old-fashioned drug store still serves sodas and lunch. Also downtown is the "World Famous Hydro Bar." The bar has been in business since the early years of Hydro and still has pictures of the old-fashioned wood swinging doors that used to be the front doors to the bar.